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Primary and Secondary Antibodies in Immunoassays
Written by: Genya Gorshtein, MSc Published: June 13, 2023 Contents Introduction How do Primary and Secondary Antibodies Work? How [...]
Antibody Developability: Sequence and Structure Impacts Antibody Aggregation
Written by: Genya Gorshtein, MSc Published: September 12, 2023 Contents Introduction Mechanisms That Influence Protein Aggregation and Stability Sequence [...]
The Basics of Protein and Antibody Glycosylation
Written by: Genya Gorshtein, MSc Published: October 18, 2023 Contents Introduction Types of Glycans How are Proteins Glycosylated? Why [...]
Affinity Maturation: How The Immune System Gets Smarter Over Time
Written by: Jenna Kerry, MSc Published: October 25, 2023 Contents Introduction What is Affinity Maturation? How Does Somatic Hypermutation [...]
Nanobody Sequencing: Unlocking Therapeutic Potential
Written by: Jenna Kerry, MSc Published: November 29, 2023 Contents Introduction Nanobody Structure Generation and Production Therapeutic and Diagnostic Applications [...]
Modifying Antibody Functions Through Glycan Engineering
Written by: Genya Gorshtein, MSc Published: January 8, 2024 Contents Introduction Glycoengineering of Therapeutic mAbs Glycoengineering Methods Informed Glycan [...]
Antibody Production: A Guide to Choosing a Recombinant Expression System
Written by: Jenna Kerry, MSc Published: February 2, 2024 Contents Introduction Recombinant Expression Systems Recombinant Expression of Polyclonal Antibodies Rapid [...]
Antibodies in Flow Cytometry – The Key to Success
Written by: Jenna Kerry, MSc Published: March 5, 2024 Contents Introduction to Flow Cytometry Understanding Flow Cytometry Interpreting Flow Cytometry [...]
Challenges of Membrane Proteins as Antigens in Antibody Drug Discovery
Written by: Genya Gorshtein, MSc Published: April 3, 2024 Contents Introduction Membrane Proteins are Difficult Antigens Strategies for Utilizing [...]
The Landscape of Bispecific and Multispecific Antibodies
Written by: Genya Gorshtein, MSc Published: April 19, 2024 Contents Introduction Bispecifics and Multispecific Antibody Formats Mechanism of Action [...]
Autoantibodies: Natural and Pathogenic
Written by: Jenna Kerry, MSc Published: May 1, 2024 Contents What are Autoantibodies? How are Autoantibodies Produced? How do Autoantibodies [...]
The Power of Recombinant Antibody Cocktails
Written by: Jenna Kerry, MSc Published: June 10, 2024 Contents Introduction Advantages of Recombinant Antibody Cocktails Recombinant Antibody Cocktail Formats [...]
Detecting and Preventing Disulfide Scrambling in Monoclonal Antibodies
Written by: Jenna Kerry, MSc Published: August 1, 2024 Contents Introduction Disulfide Bond Structure and Function in Monoclonal Antibodies Disulfide [...]
Sequence Variant Analysis of Monoclonal Antibodies
Written by: Genya Gorshtein, MSc Published: August 8, 2024 Contents Introduction What are Protein Sequence Variants Impact of Sequence [...]
Antagonistic Antibodies: Opportunities and Obstacles
Written by: Jenna Kerry, MSc Published: August 14, 2024 Contents What are Antagonistic Antibodies? How do Antagonistic Antibodies Work? Antagonistic [...]
Best Hosts for Antibody Discovery and Generation
Written by: Genya Gorshtein, MSc Published: August 26, 2024 Contents Introduction Advantages of Antibody Discovery In Diverse Species Unique [...]
Agonist Antibody Challenges and Optimization
Written by: Jenna Kerry, MSc Published: September 17, 2024 Contents Introduction Agonistic Antibody Mechanism of Action Agonistic Antibody Development Challenges [...]
Trick or Treat: Unmasking Antibody Reproducibility in Life Sciences
In this webinar, you will learn: How mAb irreproducibility could unknowingly impact your research outcomes Proven strategies to mitigate reproducibility risks when [...]
Comparing Epitope Mapping Methods
Written by: Genya Gorshtein, MSc Published: October 16, 2024 Contents Introduction Epitope Mapping Methods Addressing the Limitations of HDX-MS [...]
Antibody Humanization Strategies, Challenges, and Innovations
Written by: Jenna Kerry, MSc Published: November 6, 2024 Contents Why Humanize Antibodies? What is Antibody Humanization? Antibody Humanization Techniques [...]