November 2024

Antibody Humanization Strategies, Challenges, and Innovations

2024-11-06T17:37:43-05:00November 6th, 2024|Articles|

Written by: Jenna Kerry, MSc Published: November 6, 2024 Contents Why is Antibody Humanization Important? What is Antibody Humanization? Antibody Humanization Techniques Current Challenges of Antibody Humanization The Future of Human Antibody Therapeutics Fully Human Antibody Discovery / Human Antibody Discovery From Human Serum Why is Antibody [...]

September 2024

Agonist Antibody Challenges and Optimization

2024-10-01T17:08:33-04:00September 18th, 2024|Articles|

Written by: Jenna Kerry, MSc Published: September 17, 2024 Contents Introduction Agonistic Antibody Mechanism of Action Agonistic Antibody Development Challenges Optimizing Agonistic Antibodies Agonistic Antibody Development Introduction In the last decade, immunotherapy has rapidly transformed treatments for cancer, autoimmune disorders, and infectious diseases. While the [...]

June 2024

Epitope Mapping: Alanine Scanning Mutagenesis vs. HDX-MS

2024-06-10T13:42:22-04:00June 10th, 2024|Articles|

Written by: Genya Gorshtein, MSc Published: June 10, 2024 Contents Introduction Alanine Scanning Mutagenesis Epitope Mapping HDX-MS Epitope Mapping Antibody Epitope Mapping Services Introduction Epitope mapping elucidates the antibody function by identifying specific binding sites on the antigen that interact with the antibody. Alanine [...]