December 2024

Phage Display Antibody Discovery

2024-12-20T14:38:21-05:00December 19th, 2024|Articles|

Written by: Jenna Kerry, MSc Published: December 20, 2024 Contents What is Phage Display? How Does Phage Display Work? Phage Display Technology Advantages Phage Display Technology Limitations The Future of Phage Display Technology Overcoming Limitations of Phage Display Antibody Discovery What is Phage Display? Over [...]

B Cells and Their Antibodies

2024-12-10T10:11:07-05:00December 9th, 2024|Articles|

Written by: Genya Gorshtein, MSc Published: December 12, 2024 Contents Introduction B Cells and Their Receptors Antibodies in Serum How Do You Discover Antibodies From Serum? Introduction While B cells play a crucial role in recognizing antigens and initiating immune responses, their differentiation into [...]

B Cell Sequencing and Polyclonal Sequencing Explained

2024-12-09T17:57:13-05:00December 9th, 2024|Articles|

Written by: Genya Gorshtein, MSc Published: December 12, 2024 Contents Introduction BCR and Single B Cell Sequencing for Antibody Discovery Antibody Discovery through De Novo Sequencing of Serum Antibodies Proteogenomics: A Complimentary Approach Antibody Discovery With Rapid Novor Introduction B cell sequencing has long [...]

November 2024

Antibody Humanization Strategies, Challenges, and Innovations

2024-12-11T10:12:25-05:00November 6th, 2024|Articles|

Written by: Jenna Kerry, MSc Published: November 6, 2024 Contents Why Humanize Antibodies? What is Antibody Humanization? Antibody Humanization Techniques Current Challenges of Antibody Humanization The Future of Human Antibody Therapeutics Fully Human Antibody Discovery / Human Antibody Discovery From Human Serum Why Humanize Antibodies? [...]

October 2024

Trick or Treat: Unmasking Antibody Reproducibility in Life Sciences

2024-12-16T17:29:22-05:00October 1st, 2024|Webinars|

In this webinar, you will learn: How mAb irreproducibility could unknowingly impact your research outcomes Proven strategies to mitigate reproducibility risks when using research reagents The role of antibody sequencing in ensuring reproducibility with mAbs Rapid, cost-effective sequence confirmation for routine applications The next frontier: polyclonal antibody sequencing and recombinant pAbs [...]

September 2024

Agonist Antibody Challenges and Optimization

2024-10-01T17:08:33-04:00September 18th, 2024|Articles|

Written by: Jenna Kerry, MSc Published: September 17, 2024 Contents Introduction Agonistic Antibody Mechanism of Action Agonistic Antibody Development Challenges Optimizing Agonistic Antibodies Agonistic Antibody Development Introduction In the last decade, immunotherapy has rapidly transformed treatments for cancer, autoimmune disorders, and infectious diseases. While the [...]

August 2024

Interview with Dr. Thierry Le Bihan, Principal Scientist in Polyclonal Antibody Sequencing

2024-12-02T13:42:20-05:00August 1st, 2024|Articles|

Principal Scientist in Polyclonal Antibody Sequencing Dr. Thierry Le Bihan joined Rapid Novor as a Principal Scientist in 2018, tasked with leading a multidisciplinary team to develop a polyclonal antibody sequencing platform. Thierry brought extensive proteomics and mass spectrometry expertise from his previous roles as Director of Proteomics at The Campbell Family Institute [...]

July 2024

Antibody Discovery in Humans – Starting with Functional, Circulating Antibodies

2024-12-03T12:38:28-05:00July 23rd, 2024|Webinars|

This paper is now published in Nature Communications! Le Bihan, T., Nunez de Villavicencio Diaz, T., Reitzel, C. et al. De novo protein sequencing of antibodies for identification of neutralizing antibodies in human plasma post SARS-CoV-2 vaccination. Nat Commun 15, 8790 (2024). https://doi.org/10.1038/s41467-024-53105-8 In this webinar, you will: Explore how using a [...]