Antibody Affinity Insights with REpAb Antibody Discovery
Our client is a biotechnology company developing therapeutics that target cancer-specific carbohydrate antigens on the surface of tumour cells.
April 2025
December 2024
B Cells and Their Antibodies
Written by: Genya Gorshtein, MSc Published: December 12, 2024 Contents Introduction B Cells and Their Receptors Antibodies in Serum How Do You Discover Antibodies From Serum? Introduction While B cells play a crucial role in recognizing antigens and initiating immune responses, their differentiation into [...]
B Cell Sequencing and Polyclonal Sequencing Explained
Written by: Genya Gorshtein, MSc Published: December 12, 2024 Contents Introduction BCR and Single B Cell Sequencing for Antibody Discovery Antibody Discovery through De Novo Sequencing of Serum Antibodies Proteogenomics: A Complimentary Approach Antibody Discovery With Rapid Novor Introduction B cell sequencing has long [...]
October 2024
De Novo Protein Sequencing of Antibodies for Identification of Neutralizing Antibodies in Human Plasma Post SARS-CoV-2 Vaccination
To develop robust mAb biologics, it is vital to fully characterize the protein, including its primary sequence, mutations, and important post-translational modifications
August 2024
Interview with Dr. Thierry Le Bihan, Principal Scientist in Polyclonal Antibody Sequencing
Principal Scientist in Polyclonal Antibody Sequencing Dr. Thierry Le Bihan joined Rapid Novor as a Principal Scientist in 2018, tasked with leading a multidisciplinary team to develop a polyclonal antibody sequencing platform. Thierry brought extensive proteomics and mass spectrometry expertise from his previous roles as Director of Proteomics at The Campbell Family Institute [...]
June 2024
The Power of Recombinant Antibody Cocktails
Written by: Jenna Kerry, MSc Published: June 10, 2024 Contents Introduction Advantages of Recombinant Antibody Cocktails Recombinant Antibody Cocktail Formats Engineering Recombinant Antibody Cocktails Production of Recombinant Antibody Cocktails Recombinant Antibody Cocktail Applications Generate Antibody Cocktails with De Novo Antibody Sequencing Service Introduction Recombinant antibody [...]
July 2023
Antibody Discovery Dead Ends and New Approaches
In this webinar, you will learn: About the challenges commonly encountered in antibody discovery campaigns, including non-functional antibodies, limited diversity, developability issues, and immunogenicity. How to de-risk antibody discovery campaigns, while balancing speed and spend Discover how a proteomics and mass spectrometry-based approach to antibody discovery, utilizing REpAb polyclonal sequencing, presents [...]