August 2024

Antagonistic Antibodies: Opportunities and Obstacles

2024-12-02T13:27:16-05:00August 14th, 2024|Articles|

Written by: Jenna Kerry, MSc Published: August 14, 2024 Contents What are Antagonistic Antibodies? How do Antagonistic Antibodies Work? Antagonistic Antibody Opportunities Antagonistic Antibody Obstacles Antibody Discovery Platform for Antagonistic Antibodies What are Antagonistic Antibodies? Antagonistic antibodies are a monoclonal antibody that bind to and [...]

Sequence Variant Analysis of Monoclonal Antibodies

2024-08-09T14:29:53-04:00August 9th, 2024|Articles|

Written by: Genya Gorshtein, MSc Published: August 8, 2024 Contents Introduction What are Protein Sequence Variants Impact of Sequence Variants on Monoclonal Antibodies Challenges in Sequence Variant Analysis and Detection Sequence Variant Analysis Service Introduction Sequence variants are unwanted impurities in antibody and biotherapeutic [...]

Detecting and Preventing Disulfide Scrambling in Monoclonal Antibodies

2024-12-02T13:40:48-05:00August 6th, 2024|Articles|

Written by: Jenna Kerry, MSc Published: August 1, 2024 Contents Introduction Disulfide Bond Structure and Function in Monoclonal Antibodies Disulfide Scrambling in Monoclonal Antibodies Impact of Disulfide Bonds on Monoclonal Antibodies Strategies to Prevent Disulfide Scrambling in Monoclonal Antibodies Disulfide Bond Analysis for Monoclonal Antibodies Introduction [...]